Long-term Outcomes of Keratolimbal Allograft for Total Limbal Stem Cell Deficiency Using Combined Immunosuppressive Agents and Correction of Ocular Surface Deficits

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Long-term outcomes of keratolimbal allograft for total limbal stem cell deficiency using combined immunosuppressive agents and correction of ocular surface deficits.

OBJECTIVE To determine the long-term outcomes of keratolimbal allograft (KLAL). METHODS Scores of such risks as infrequent blinking, blink-related microtrauma, conjunctival inflammation, elevated intraocular pressure, dry eye, symblepharon, lagophthalmos, and previous KLAL or penetrating keratoplasty (PKP) failure were calculated and recorded before, during, and after KLAL. Prolonged oral myc...

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keratolimbal allograft in total limbal stem cell deficiency

purpose: to investigate the outcomes of keratolimbal allograft (klal) for treatment of total limbal stem cell deficiency (lscd). method: patients with total lscd and adequate tear production were included. a total of 27 klal procedures were performed in 21 eyes of 20 patients with lscd. immunosuppression was achived using mycophenolate and cyclosporine. main outcome measure was improvement in v...

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Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency.

PURPOSE To evaluate the long-term outcome of ocular surface reconstruction, including keratolimbal allograft (KLAL) and amniotic membrane transplantation (AMT) with or without penetrating keratoplasty (PKP), in patients with nonambulatory vision secondary to total limbal stem cell deficiency (LSCD). DESIGN Retrospective, non-comparative interventional case series. PARTICIPANTS Thirty-nine e...

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Long-term Outcome of Limbal Stem Cell Transplantation for the Management of Total Limbal Stem Cell Deficiency due to a Chemical Burn

Purpose: To evaluate the long-term outcome of limbal stem cell transplantation (LSCT) for the management of total limbal stem cell deficiency (LSCD) due to chemical burn in Labbafinejad Medical Center (LMC). Methods: Records of patients with a history of severe (i.e. grade III and IV) chemical burns, who were referred to LMC and underwent LSCT, were reviewed and data including demographic chara...

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Long-term outcomes of keratolimbal allograft for the treatment of severe ocular surface disorders.

PURPOSE To investigate the long-term outcome of keratolimbal allograft (KLAL) for the treatment of severe ocular surface disorders. DESIGN Retrospective, noncomparative case series. PARTICIPANTS Twenty patients (23 eyes) with severe ocular surface disorders. INTERVENTION Thirty-three KLAL procedures were performed. Ten patients (10 eyes) underwent KLAL in combination with other surgical p...

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 2009

ISSN: 0003-9950

DOI: 10.1001/archophthalmol.2009.263